Lung diseases face a serious threat to human health around the world. Inhaled particles are often the source of disease (viruses, bacteria, carcinogens), but could also be the source of an effective treatment should a drug be formulated as an aerosol. To understand the behavior of disease inception and how an aerosol could be deployed to treat it, we have built a computational fluid dynamics model of the airways. The simulation domain includes the physics of both airflow and the mucociliary clearance mechanism, and how these fluids impact the distribution of aerosolized particles.